Covance Laboratories

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Covance Laboratories is an international contract research organization (CRO) and laboratory animal breeding company. Firms hire CROs to conduct animal toxicity tests for agrochemicals, petrochemicals, household products, pharmaceutical drugs and toxins. Covance has its headquarters in Princeton, New Jersey and facilities in over 25 countries with over 9,800 employees world wide. A division of the company called Covance Research Products (CRP) based in Denver, Pennsylvania, imports, breeds and sells laboratory animals. CRP provides canines, rabbits and primates for laboratories and has created and trademarked new breeds of animals, including the "Mini-Mongrel dog". Covance is the largest importer of primates in the U.S. and the world's largest breeder of laboratory dogs.

Covance & the tobacco industry

Council for Tobacco Research & National Cancer Institute

Under its former name of Hazleton Laboratories, Covance was associated with the Council for Tobacco Research and conducted animal testing for tobacco companies. In September of 1972, Carl Baker, the former chairman of the National Cancer Institute (NCI), became the president of Hazleton Laboratories. Hazleton was a "major research contractor" for NCI and had been conducting chemosol treated cigarette studies for "tar" tumorigenicity for nine U.S. cigarette manufacturers since 1970.

NCI sponsored study: smoking beagles

In an NCI sponsored study, Hazleton provided animal data favorable to the tobacco industry that contributed to the continued marketing of cigarettes. Between February of 1978 and March of 1980, Hazleton conducted a two-year study of for NCI on the the cardiovascular effects of mainstream cigarette smoke and carbon monoxide on "204 permanently tracheostomized male beagle" dogs. The dogs were forced to inhale all of the mainstream smoke generated by six cigarettes a day while being fed diets of varying levels of cholesterol. A number of dogs died during the study. The study concluded that smoking may have "a possible protective effect" and "lent no support to the suggestion that cigarette smoking increases the rate of development of atherosclerosis." <tdo>resource_id=6797 resource_code=hazlton_labs search_term=Hazelton Laboratories</tdo>

Second hand smoke studies

In the 1990s, Covance performed studies sponsored by the tobacco industry claiming that even extreme exposure to secondhand smoke was safe for humans. According to the Surgeon General of the United States Public Health Service, secondhand smoke substantially increases the risks of lung cancer and heart disease. Covance internal documents from 2002 discuss a "Philip Morris/Covance Project Team" for studies. At a November 2005 tobacco trade-group conference in Manila, Philippines, Covance's presentation was entitled: How Can Covance Support Research and Development Needs of the Tobacco Industry?

See also animal testing, section 5 on tobacco studies.

Philip Morris

The Altria Group is a parent company whose primary holdings include the Philip Morris companies and which formerly included Kraft Foods. The Altria Group is a client of Covance Laboratories.

Animal testing: overview

Animals by species, numbers & locations

• Vienna, Virginia

• Madison, Wisconsin

• Denver, Pennsylvania

Biomedical research facilities and copies of USDA reports by state

For links to copies of this facility's U.S. Department of Agriculture reports indicating species, number of animals used and other information visit Stop Animal Experimentation Now Facility Reports and Information, U.S. Department of Agriculture-Animal Plant Health Inspection reports. This Web site lists each of the 50 states; each state's name links to biomedical research facilities in that state, and to PDF copies of government documents where the facilities must report their animal usage.

Animal cruelty & welfare reports: overview

Stop Animal Exploitation Now! (SAEN) is a national research watchdog organization. SAEN has included Covance Laboratories among the worst violators of U.S. laws. Covance amassed a combined 42 violations between their Pennsylvania and Virginia laboratories, including the starving of dogs and failure to provide veterinary care for broken bones. (Government reports and ranking statistics available upon request.)

Animal welfare investigations: United States

Denver, Pennsylvania

In 2004 and 2005, the Denver, PA Covance facility amassed 27 violations in the areas of veterinary care, housing and Institutional Animal Care and Use Committee (IACUC) violations. Incidents at this Covance facility caused intense suffering to rabbits, pigs and dogs documented by attending veterinarians and the IACUC. Incidents included placing dogs and pigs in food restrictive devices resulting in severe weight loss and inadequate post surgical care for rabbits.

Vienna, Virginia

For a 6 month period from April 26, 2004, to March 11, 2005, an undercover investigator from People for the Ethical Treatment of Animals (PETA) videotaped systematic abuse of animals at Covance Laboratories' facility in Vienna, Virginia. The investigator's video described the laboratory as a documentation of "terror, sadness, sickness, injuries, suffering, and death" (of monkeys from the wild and Covance breeding facilities). According to the investigator, animal technicians referred to the head veterinarian as "Mr. Let's Wait and See." Primate staff (even those who often abused monkeys) complained repeatedly about a young monkey left in his cage with a broken arm for four days. The break was so severe, that the monkey later had to be euthanized on the advice of a veterinarian who returned from "time off", after this period. The only pain medication it received during the four days was a mild aspirin equivalent. PETA filed a 273-page complaint with the USDA detailing violations of the federal Animal Welfare Act (AWA)., ,

Short list of FD&C Act violations for Vienna, Virginia facility

The following is a short list of the over 100 violations of the Federal Food, Drug and Cosmetic Act (FD&C Act) for Covance's facility in Vienna, Virginia. These violations and this video led to investigations by the Food and Drug Administration (FDA) and the U.S. Department of Agriculture (USDA) for violations of the AWA.

• "Striking, choking, screaming and cursing at "uncooperative", frightened and sick monkeys.
• Slamming monkeys into their cages after they've had dosing tubes inserted down their noses and throats.
• Hosing down cages with sick, injured or recovering monkeys and/or dogs still inside.
• Slamming cages to terrorize loose monkeys out of hiding. Slamming the head of an escaped monkey against concrete.
• Denial of veterinary care and deaths in drug tests in which the veterinarian was forbidden to examine, treat or euthanize.
• Inappropriate sized dosing tubes - small monkeys dosed with large tubes forced up their nostrils and down into their stomachs, causing choking, gagging, and daily bloody noses.
• Self-mutilation resulting from Covance's failure to provide psychological enrichment and socialization.
• Injuries left untreated until they became necrotic. Broken arm untreated for 4 days.
• Non-stop blaring loud rock music, creating discomfort and alarm.
• Physical and psychological abuse of primates falling outside of the written study parameters.
• Falsifying records to cover up problems with the health of study animals and worker incompetence.
• Lack of employee training and supervision. Uncertified employees anesthetizing animals.
• Teasing, taunting, and yelling at primates for amusement.
• Knowingly using unhealthy animals in studies.
• Painful procedures performed in full view of other primates. Improperly grounded medical equipment burning research animals.
• During new technician training the new employees were told that there is nothing wrong with screaming or cursing at the monkeys, and forcing the monkeys to "dance"'
• Removing the quarantine sign from the quarantine room so that employees did not have to wear the required medical protection gowns.
• Intoxicated employees performing lab procedures on monkeys.
• Covance research director not euthanizing sick monkeys when directed to do so by the veterinarian.
• Failure to isolate imported primates. Malaria-infected monkeys still used in studies for pharmaceuticals.
• Lying about the cause of death for three monkeys found dead in their cages."

USDA reports

• Nov 2001, Inspection ID 174066
• Nov 2001, Inspection ID 174065
• Jan 2005, Inspection ID 233130
• Jan 2005, Inspection ID 172320
• Feb 2005, Inspection ID 120580
• Feb 2005, Inspection ID 109674
• May 2005, Inspection ID 233167
• June 2005, Inspection ID 172307
• August 2005, Inspection ID 213216
• August 2005, Inspection ID 213220
• Covance / USDA Settlement Agreement.

Animal welfare investigations: Europe

Munster, Germany

For five months in 2003, the British Union for the Abolition of Vivisection (BUAV) sent German journalist Friedrich Mülln to work undercover in the Covance facility in Münster, Germany, Europe's largest primate-testing center. Mülln obtained photographs, video, and other evidence of primate abuse. The laboratory specializes in toxicology and tests on pregnant primates. The undercover footage revealed staff forcing monkeys to "dance" to blaring music, rough handlilng and screaming at primates. Primates were filmed living in isolation in small, wire cages with little or no natural light and high noise levels (between loud radios and the yelling of staff).

Local authorities inspected the Munster facility after video footage was shown on German television and insisted video cameras be installed to monitor staff working with primates. Covance won a subsequent appeal, arguing that video monitoring would "infringe the rights of the staff". The public prosecutor's office concluded that Covance "had not rendered themselves liable to prosecution," and cleared them of all charges.

Attempt to stop airing videos in Europe

Covance also filed a lawsuit to forbid further distribution of material. The ban sparked major protests from animal rights and anti-censorship activists. Covance's claims were partially revoked by a higher court, citing the public's right to information over the company's "privacy". The court decided that the video footage could be aired publicly (in a different format and not by animal rights groups). Covance also pressured the BUAV's internet provider to against carrying video and photographs of the investigation. See also video clip of European investigation.

Covance also filed a lawsuit to prevent PETA from airing video footage of their investigation in Europe. However, the judge ruled in PETA's favor. According to Hon. Peter Langan of the United Kingdom, the rough manner and bleak surroundings "cried out for explanation, even to a viewer with no particular interest in animal welfare". Covance Laboratories Limited v. PETA Europe Limited was filed in the High Court of Justice, Chancery Division, Leeds District Registry, Claim No. 5C-00295. The court also ordered Covance to pay PETA £50,000 in costs and fees.

Five year ban on infiltration

Covance Laboratories subsequently filed a lawsuit against PETA and it's operative, Lisa Leitten. In October of 2005, PETA agreed to a ban on conducting any infiltration of Covance for five years. Lisa Leitten agreed to a three year ban on infiltrating any commercial animal research facility worldwide. PETA and Leitten also agreed not to publish or share videos or written materials taken from Covance. The settlement was confirmed by the Circuit Court of Fairfax County, Virginia.

Lobbying & public relations

In the fiscal year ending in 2008, Covance paid $100,000 to Policy Directions Inc.

Finances

Covances' annual revenues for the fiscal year ending in 2008 exceeded 1.7 billion dollars.

Executive board

• Joseph Herring, Chairman & Chief Executive Officer
  
• Wendel Barr, Executive Vice President & Chief Operating Officer
  
• William Klitgaard, Corporate Senior Vice President & Chief Financial Officer
  

Contact

United States 888-268-2623
Europe 609-419-2240
Africa 800-2682-2682
Asia/Pacific 800-6568-3000

Website: http://www.covance.com/

Articles & sources

SourceWatch resources

• Altria Group
• Animal testing
• Council for Tobacco Research
• National Cancer Institute
• Policy Directions Inc.
• Tobacco industry
• Pharmaceutical industry
• U.S. Government's War on Animals
• Surgeon General of the United States Public Health Service
• People for the Ethical Treatment of Animals
• Richard Berman cares about animals: clients exposed

External articles

• Micheal Budkie The Routine Agony of Neglected Animals in Laboratories, Stop Animal Exploitation Now!, accessed June 2009
• Training Terrorists, People for the Ethical Treatment of Animals, accessed February 2009
• Transported from Purgatory Back to Hell Again, PETA.org, accessed February 2009
• Cruel Tests for Profit: The Grease Pit, PETA.org, accessed February 2009
• What the Investigator Saw, PETA.org, accessed February 2009
• What the Investigator Heard, PETA.org, accessed February 2009
• Covance Cruelty Videos, PETA.org, accessed February 2009